TPDB

3D PDB MODEL

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TPDB ID TPDB53318

Peptide_Name

PENK(239-260)

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 22-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

FAESLPSDEEGESYSKEVPEME

FASTA

>TPDB53318|Neuropeptide|length=22
FAESLPSDEEGESYSKEVPEME

Formula C106H157N23O44S1

Absent Amino Acids RNCQHITW

Common Amino Acids E

Mass 2489.60

PI 3.38

Basic Residues 1

Acidic Residues 8

Hydrophobic Residues 6

Net Charge -7

Boman Index 14.83

Hydrophobicity -1.159

Aliphatic Index 35.45

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 1490

Absorbance 280nm 59.85

Polar Residues 5

number

1

A

0

R

0

N

1

D

0

C

7

E

0

Q

1

G

0

H

0

I

1

L

1

K

1

M

1

F

2

P

4

S

0

T

0

W

1

Y

1

V

Amino Acid Distribution

A: 1 R: 0 N: 0 D: 1 C: 0 E: 7 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 1 M: 1 F: 1 P: 2 S: 4 T: 0 W: 0 Y: 1 V: 1

Length

22

Formula

C106H157N23O44S1

Mass

2489.60

PI

3.38

Net Charge

-7

Boman Index

14.83

Hydrophobicity

-1.159

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Delta-type opioid receptor

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Opioid

Receptor Lengths 372

Receptor Ligands NP07976 NP08008 NP08014 NP08030 NP08037 NP08043 NP08071 NP08084 NP08242 NP08117 NP08125 NP08133 NP08166 NP08172 NP08178 NP08250 NP08078 NP07992 NP08102

Family

Opioid

Receptor_Lengths

372

Receptor_Ligands

NP07976 NP08008 NP08014 NP08030 NP08037 NP08043 NP08071 NP08084 NP08242 NP08117 NP08125 NP08133 NP08166 NP08172 NP08178 NP08250 NP08078 NP07992 NP08102