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Peptide record

TPDB53208

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Neuropeptide Umami iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB53208
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Neuropeptide Umami iDPPIV
Cardiometabolic peptides Neuroactive peptides Food sensory peptides
Peptipedia Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (Neuropeptide, Umami, and iDPPIV) peptide sequence curated from Peptipedia, Tastepeptides-Meta, and iDPPIV, with an available 3D structural model.
Sequence
ES
Physicochemical Analysis
C8H14N2O6
ARNDCQGHILKMFPTWYV
ES
234.21
3.29
0
1
0
-1
2.15
-2.150
0.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C8H14N2O6
234.21
3.29
-1
2.15
-2.150
234.2060
234.0848
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73
2015
Journal

Other

2
BIOPEP database of bioactive peptides SMILES: N[C@H](C(=O)N[C@H](C(=O)O)CO)CCC(=O)O InChI=1S/C8H14N2O6/c9-4(1-2-6(12)13)7(14)10-5(3-11)8(15)16/h4-5,11H,1-3,9H2,(H,10,14)(H,12,13)(H,15,16)/t4-,5-/m0/s1 InChIKey: UQHGAYSULGRWRG-WHFBIAKZSA-N Umami peptide according to BIOPEP database of sensory peptides and amino acids (ID 332) Bitterness suppressing peptide according to BIOPEP database of sensory peptides and amino acids (ID 333)
Additional Detail Fields 1 fields
2