TPDB

3D PDB MODEL

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TPDB ID TPDB52963

Peptide_Name

Neuropeptide-glutamic acid-isoleucine

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 13-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

EIGDEENSAKFPI

FASTA

>TPDB52963|Neuropeptide|length=13
EIGDEENSAKFPI

Formula C63H97N15O24

Absent Amino Acids RCQHLMTWYV

Common Amino Acids E

Mass 1448.55

PI 3.69

Basic Residues 1

Acidic Residues 4

Hydrophobic Residues 4

Net Charge -3

Boman Index 7.37

Hydrophobicity -0.815

Aliphatic Index 67.69

Half Life

Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 2

number

1

A

0

R

1

N

1

D

0

C

3

E

0

Q

1

G

0

H

2

I

0

L

1

K

0

M

1

F

1

P

1

S

0

T

0

W

0

Y

0

V

Amino Acid Distribution

A: 1 R: 0 N: 1 D: 1 C: 0 E: 3 Q: 0 G: 1 H: 0 I: 2 L: 0 K: 1 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0

Length

13

Formula

C63H97N15O24

Mass

1448.55

PI

3.69

Net Charge

-3

Boman Index

7.37

Hydrophobicity

-0.815

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Canis lupus familiaris

Family Melanin-concentrating hormone

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Melanin-concentrating hormone receptor 1 Melanin-concentrating hormone receptor 2

Receptor Organisms Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Melanin-concentrating hormone

Receptor Lengths 422 340

Receptor Ligands NP05382 NP05398 NP05409 NP05414 NP05382 NP05398 NP05409 NP05414

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Melanin-concentrating hormone receptor 1

Receptor Organisms Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Melanin-concentrating hormone

Receptor Lengths 353

Receptor Ligands NP05383 NP05399 NP05410 NP05416 NP05421

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Melanin-concentrating hormone receptor 1

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Melanin-concentrating hormone

Receptor Lengths 353

Receptor Ligands NP05394 NP05385 NP05400 NP05411 NP05420 NP05422 NP05423

Family

Melanin-concentrating hormone

Receptor_Lengths

422 340 353

Receptor_Ligands

NP05382 NP05398 NP05409 NP05414 NP05383 NP05399 NP05410 NP05416 NP05421 NP05394 NP05385 NP05400 NP05411 NP05420 NP05422 NP05423