TPDB

3D PDB MODEL

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TPDB ID TPDB52764

Peptide_Name

Relaxin-3 A chain

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 24-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

DVLAGLSSSCCEWGCSKSQISSLC

FASTA

>TPDB52764|Neuropeptide|length=24
DVLAGLSSSCCEWGCSKSQISSLC

Formula C100H163N27O37S4

Absent Amino Acids RNHMFPTY

Common Amino Acids S

Mass 2463.79

PI 4.07

Basic Residues 1

Acidic Residues 2

Hydrophobic Residues 7

Net Charge -1

Boman Index 0.85

Hydrophobicity 0.425

Aliphatic Index 81.25

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 5750

Absorbance 280nm 233.38

Polar Residues 12

number

1

A

0

R

0

N

1

D

4

C

1

E

1

Q

2

G

0

H

1

I

3

L

1

K

0

M

0

F

0

P

7

S

0

T

1

W

0

Y

1

V

Amino Acid Distribution

A: 1 R: 0 N: 0 D: 1 C: 4 E: 1 Q: 1 G: 2 H: 0 I: 1 L: 3 K: 1 M: 0 F: 0 P: 0 S: 7 T: 0 W: 1 Y: 0 V: 1

Length

24

Formula

C100H163N27O37S4

Mass

2463.79

PI

4.07

Net Charge

-1

Boman Index

0.85

Hydrophobicity

0.425

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Relaxin-3 receptor 1 Relaxin-3 receptor 2 Relaxin receptor 1 Relaxin receptor 2

Receptor Organisms Mus musculus Mus musculus Mus musculus Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Insulin

Receptor Lengths 472 414 758 737

Receptor Ligands NP05209 NP05214 NP05209 NP05214 NP05097 NP05094 NP05172 NP05190 NP05209 NP05214 NP05172 NP05190 NP05209 NP05214 NP05024

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Relaxin receptor 1

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Insulin

Receptor Lengths 758

Receptor Ligands NP05174 NP05192 NP05212 NP05217

Family

Insulin

Receptor_Lengths

472 414 758 737

Receptor_Ligands

NP05209 NP05214 NP05097 NP05094 NP05172 NP05190 NP05024 NP05174 NP05192 NP05212 NP05217