TPDB

3D PDB MODEL

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TPDB ID TPDB52606

Peptide_Name

DPKQDFMRF-amide FMRFa-2 FMRFamide-2

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 9-aa standard natural neuropeptide peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

DPKQDFMRF

FASTA

>TPDB52606|Neuropeptide|length=9
DPKQDFMRF

Formula C53H78N14O15S1

Absent Amino Acids ANCEGHILSTWYV

Common Amino Acids DF

Mass 1183.35

PI 6.90

Basic Residues 2

Acidic Residues 2

Hydrophobic Residues 3

Net Charge -0

Boman Index 2.80

Hydrophobicity -1.444

Aliphatic Index 0.00

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 1

number

0

A

1

R

0

N

2

D

0

C

0

E

1

Q

0

G

0

H

0

I

0

L

1

K

1

M

2

F

1

P

0

S

0

T

0

W

0

Y

0

V

Amino Acid Distribution

A: 0 R: 1 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0

Length

9

Formula

C53H78N14O15S1

Mass

1183.35

PI

6.90

Net Charge

-0

Boman Index

2.80

Hydrophobicity

-1.444

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names FMRFamide receptor

Receptor Organisms Drosophila melanogaster

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Drosophila melanogaster

Family FMRFamide related peptide

Receptor Lengths 549

Receptor Ligands NP03364 NP02606 NP02648 NP02654 NP03172 NP03460 NP03583 NP03654 NP03660 NP03729 NP03743

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Drosophila virilis

Family FMRFamide related peptide

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Neuropeptide SIFamide receptor

Receptor Organisms Drosophila melanogaster

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Drosophila melanogaster

Family FMRFamide related peptide

Receptor Lengths 758

Receptor Ligands NP03688 NP03576 NP03080 NP03531

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Drosophila mojavensis

Family FMRFamide related peptide

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Drosophila pseudoobscura

Family FMRFamide related peptide

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Drosophila sechellia

Family FMRFamide related peptide

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Drosophila suzukii

Family FMRFamide related peptide

Family

FMRFamide related peptide

Receptor_Lengths

549 758

Receptor_Ligands

NP03364 NP02606 NP02648 NP02654 NP03172 NP03460 NP03583 NP03654 NP03660 NP03729 NP03743 NP03688 NP03576 NP03080 NP03531