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Peptide record

TPDB52193

Oxytocin Blood-Brain Barrier Neuropeptide standard

9 amino acids

3D PDB MODEL

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TPDB ID TPDB52193

Peptide_Name

Oxytocin

Activity

Blood-Brain Barrier Neuropeptide

Activity_category_statistics

Delivery and barrier-penetrating peptides Neuroactive peptides

Database_Source

B3Pred BBPpredict Peptipedia PEPlife

Sequence_Type

standard

Has_Modification No

Description A 9-aa standard natural multi-activity (Blood-Brain Barrier and Neuropeptide) peptide sequence curated from B3Pred, BBPpredict, Peptipedia, and other sources, with an available 3D structural model.

Sequence

CYIQNCPLG

FASTA

>TPDB52193|Blood-Brain Barrier;Neuropeptide|length=9
CYIQNCPLG

Formula C43H67N11O13S2

Absent Amino Acids ARDEHKMFSTWV

Common Amino Acids C

Mass 1010.19

PI 5.18

Basic Residues 0

Acidic Residues 0

Hydrophobic Residues 3

Net Charge -0

Boman Index -0.83

Hydrophobicity 0.333

Aliphatic Index 86.67

Half Life

Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1615

Absorbance 280nm 159.87

Polar Residues 5

number

Amino Acid Distribution

A: 0 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0

Length

Formula

C43H67N11O13S2

Mass

1010.19

5.18

Net Charge

-0

Boman Index

-0.83

Hydrophobicity

0.333

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Achatina fulica

Family Vasopressin/oxytocin

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Balaenoptera physalus

Family Vasopressin/oxytocin

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Oxytocin receptor

Receptor Organisms Bos taurus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family Vasopressin/oxytocin

Receptor Lengths 391

Receptor Ligands NP11191

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Hippopotamus amphibius

Family Vasopressin/oxytocin

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Equus caballus

Family Vasopressin/oxytocin

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Oxytocin receptor

Receptor Organisms Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Vasopressin/oxytocin

Receptor Lengths 389

Receptor Ligands NP11093 NP11194

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Oxytocin receptor

Receptor Organisms Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Vasopressin/oxytocin

Receptor Lengths 388

Receptor Ligands NP11195

Evidence 8 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Oxytocin receptor

Receptor Organisms Sus scrofa

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Sus scrofa

Family Vasopressin/oxytocin

Receptor Lengths 386

Receptor Ligands NP11197

Evidence 9 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Oryctolagus cuniculus

Family Vasopressin/oxytocin

Evidence 10 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Oxytocin receptor

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Vasopressin/oxytocin

Receptor Lengths 388

Receptor Ligands NP11199

Evidence 11 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Oxytocin receptor

Receptor Organisms Ovis aries

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Ovis aries

Family Vasopressin/oxytocin

Receptor Lengths 391

Receptor Ligands NP11200

Evidence 12 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Tachyglossus aculeatus aculeatus

Family Vasopressin/oxytocin

Evidence 13 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Hydrolagus colliei

Family Vasopressin/oxytocin

Experiment context

1-6 min

Family

Vasopressin/oxytocin

Half-life seconds

210.0

Half-life unit

min

Hydrophobicity

-2.7

Molecular Weight (Daltons)

1007.187

5.51

Receptor_Lengths

391 389 388 386

Receptor_Ligands

NP11191 NP11093 NP11194 NP11195 NP11197 NP11199 NP11200