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Peptide record

TPDB50658

Somatostatin Somatostatin-28 Neuropeptide standard

28 amino acids

3D PDB MODEL

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TPDB ID TPDB50658

Peptide_Name

Somatostatin Somatostatin-28

Activity

Neuropeptide

Activity_category_statistics

Neuroactive peptides

Database_Source

pep-lab Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 28-aa standard natural neuropeptide peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.

Sequence

SANSNPAMAPRERKAGCKNFFWKTFTSC

FASTA

>TPDB50658|Neuropeptide|length=28
SANSNPAMAPRERKAGCKNFFWKTFTSC

Formula C137H209N41O39S3

Absent Amino Acids DQHILYV

Common Amino Acids A

Mass 3150.60

PI 10.32

Basic Residues 5

Acidic Residues 1

Hydrophobic Residues 9

Net Charge +4

Boman Index 2.82

Hydrophobicity -0.732

Aliphatic Index 14.29

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 5625

Absorbance 280nm 178.54

Polar Residues 10

number

Amino Acid Distribution

A: 4 R: 2 N: 3 D: 0 C: 2 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 3 M: 1 F: 3 P: 2 S: 3 T: 2 W: 1 Y: 0 V: 0

Length

Formula

C137H209N41O39S3

Mass

3150.60

10.32

Net Charge

Boman Index

2.82

Hydrophobicity

-0.732

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Somatostatin

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 2 Somatostatin receptor type 5

Receptor Organisms Bos taurus Bos taurus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family Somatostatin

Receptor Lengths 368 368

Receptor Ligands NP10327 NP10360 NP10327 NP10360

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2

Receptor Organisms Canis lupus familiaris Canis lupus familiaris

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Canis lupus familiaris

Family Somatostatin

Receptor Lengths 391 369

Receptor Ligands NP10361 NP10328 NP10361 NP10328

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 5

Receptor Organisms Homo sapiens Homo sapiens Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Somatostatin

Receptor Lengths 391 369 418 364

Receptor Ligands NP10291 NP10290 NP10330 NP10363 NP10291 NP10290 NP10330 NP10363 NP10291 NP10290 NP10330 NP10363 NP10291 NP10290 NP10330 NP10363

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Macaca fascicularis

Family Somatostatin

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 5

Receptor Organisms Mus musculus Mus musculus Mus musculus Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Somatostatin

Receptor Lengths 391 369 428 362

Receptor Ligands NP10333 NP10365 NP10333 NP10365 NP10333 NP10365 NP10365

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 2

Receptor Organisms Sus scrofa

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Sus scrofa

Family Somatostatin

Receptor Lengths 369

Receptor Ligands NP10366 NP10336

Evidence 8 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 5

Receptor Organisms Rattus norvegicus Rattus norvegicus Rattus norvegicus Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Somatostatin

Receptor Lengths 391 369 428 363

Receptor Ligands NP10369 NP10337 NP10367 NP10369 NP10337 NP10367 NP10369 NP10337 NP10367 NP10369 NP10367

Evidence 9 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Ovis aries

Family Somatostatin

Family

Somatostatin

Receptor_Lengths

368 391 369 418 364 428 362 363

Receptor_Ligands

NP10327 NP10360 NP10361 NP10328 NP10291 NP10290 NP10330 NP10363 NP10333 NP10365 NP10366 NP10336 NP10369 NP10337 NP10367