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Peptide record

TPDB50638

Somatostatin 14 Somatostatin-1 Somatostatin-14 Blood-Brain Barrier Neuropeptide standard

14 amino acids

3D PDB MODEL

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TPDB ID TPDB50638

Peptide_Name

Somatostatin 14 Somatostatin-1 Somatostatin-14

Activity

Blood-Brain Barrier Neuropeptide

Activity_category_statistics

Delivery and barrier-penetrating peptides Neuroactive peptides

Database_Source

B3Pred BBPpredict Peptipedia pep-lab

Sequence_Type

standard

Has_Modification No

Description A 14-aa standard natural multi-activity (Blood-Brain Barrier and Neuropeptide) peptide sequence curated from B3Pred, BBPpredict, Peptipedia, and other sources, with an available 3D structural model.

Sequence

AGCKNFFWKTFTSC

FASTA

>TPDB50638|Blood-Brain Barrier;Neuropeptide|length=14
AGCKNFFWKTFTSC

Formula C76H106N18O19S2

Absent Amino Acids RDEQHILMPYV

Common Amino Acids F

Mass 1639.91

PI 9.11

Basic Residues 2

Acidic Residues 0

Hydrophobic Residues 5

Net Charge +2

Boman Index -3.07

Hydrophobicity 0.029

Aliphatic Index 7.14

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 5625

Absorbance 280nm 343.01

Polar Residues 6

number

Amino Acid Distribution

A: 1 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 3 P: 0 S: 1 T: 2 W: 1 Y: 0 V: 0

Length

Formula

C76H106N18O19S2

Mass

1639.91

9.11

Net Charge

Boman Index

-3.07

Hydrophobicity

0.029

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Lampetra fluviatilis

Family Somatostatin

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Oryzias latipes

Family Somatostatin

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Anguilla anguilla

Family Somatostatin

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Myoxocephalus scorpius

Family Somatostatin

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Oncorhynchus kisutch

Family Somatostatin

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Alligator mississippiensis

Family Somatostatin

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 2 Somatostatin receptor type 5

Receptor Organisms Bos taurus Bos taurus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family Somatostatin

Receptor Lengths 368 368

Receptor Ligands NP10327 NP10360 NP10327 NP10360

Evidence 8 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2

Receptor Organisms Canis lupus familiaris Canis lupus familiaris

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Canis lupus familiaris

Family Somatostatin

Receptor Lengths 391 369

Receptor Ligands NP10361 NP10328 NP10361 NP10328

Evidence 9 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Gallus gallus

Family Somatostatin

Evidence 10 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5

Receptor Organisms Homo sapiens Homo sapiens Homo sapiens Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Somatostatin

Receptor Lengths 391 369 418 388 364

Receptor Ligands NP10291 NP10290 NP10330 NP10363 NP10291 NP10290 NP10330 NP10363 NP10291 NP10290 NP10330 NP10363 NP10291 NP10290 NP10330 NP10291 NP10290 NP10330 NP10363

Evidence 11 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Macaca fascicularis

Family Somatostatin

Evidence 12 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4

Receptor Organisms Mus musculus Mus musculus Mus musculus Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Somatostatin

Receptor Lengths 391 369 428 385

Receptor Ligands NP10333 NP10365 NP10333 NP10365 NP10333 NP10365 NP10333

Evidence 13 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Myxine glutinosa

Family Somatostatin

Evidence 14 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 2

Receptor Organisms Sus scrofa

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Sus scrofa

Family Somatostatin

Receptor Lengths 369

Receptor Ligands NP10366 NP10336

Evidence 15 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4

Receptor Organisms Rattus norvegicus Rattus norvegicus Rattus norvegicus Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Somatostatin

Receptor Lengths 391 369 428 384

Receptor Ligands NP10369 NP10337 NP10367 NP10369 NP10337 NP10367 NP10369 NP10337 NP10367 NP10337

Evidence 16 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Ovis aries

Family Somatostatin

Evidence 17 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Trachemys scripta

Family Somatostatin

Evidence 18 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Amia calva

Family Somatostatin

Evidence 19 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Ictalurus punctatus

Family Somatostatin

Evidence 20 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Lophius americanus

Family Somatostatin

Evidence 21 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Pelophylax ridibundus

Family Somatostatin

Evidence 22 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Protopterus annectens

Family Somatostatin

Evidence 23 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Carassius auratus

Family Somatostatin

Family

Somatostatin

Receptor_Lengths

368 391 369 418 388 364 428 385 384

Receptor_Ligands

NP10327 NP10360 NP10361 NP10328 NP10291 NP10290 NP10330 NP10363 NP10333 NP10365 NP10366 NP10336 NP10369 NP10337 NP10367