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Peptide record

TPDB50601

Neuromedin B Neuromedin-B Blood-Brain Barrier Neuropeptide standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB50601
Neuromedin B Neuromedin-B
Blood-Brain Barrier Neuropeptide
Delivery and barrier-penetrating peptides Neuroactive peptides
B3Pred BBPpredict Peptipedia pep-lab
standard
No
A 10-aa standard natural multi-activity (Blood-Brain Barrier and Neuropeptide) peptide sequence curated from B3Pred, BBPpredict, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GNLWATGHFM
Physicochemical Analysis
C52H72N14O13S1
RDCEQIKPSYV
G
1133.29
7.85
1
0
5
+0
-2.40
0.120
49.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
485.31
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
1
L
0
K
1
M
1
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 1 K: 0 M: 1 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C52H72N14O13S1
1133.29
7.85
+0
-2.40
0.120
Linear
Similarity
Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2
Evidence Records 8 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
77.16%

Assay & Model

Capillary depletion
Origin/Source
% parenchyma

Source & Reference

NA
B3Pdb

Other

human
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
77.16%

Assay & Model

Capillary depletion
Origin/Source
% capillary

Source & Reference

NA
B3Pdb

Other

human
Direct iodination
Evidence 3 Activity

Activity

Blood-Brain Barrier
0.00012 mL/(g x min)

Assay & Model

Origin/Source
Unidirectional influx rate constant

Source & Reference

NA
B3Pdb

Other

human
Intravenous
Permeability
Direct iodination
Evidence 4 Activity

Activity

Blood-Brain Barrier
0.00799 ml/g

Assay & Model

Origin/Source
Initial disrobution volume

Source & Reference

NA
B3Pdb

Other

human
Intravenous
Permeability
Direct iodination
Evidence 5 Activity

Activity

Neuropeptide

Source & Reference

NA
NeuroPepV2

Other

Bos taurus
Bombesin/neuromedin-B/ranatensin
Evidence 6 Activity

Activity

Neuropeptide

Target

Neuromedin-B receptor
Homo sapiens

Source & Reference

NA
NeuroPepV2

Other

Homo sapiens
Bombesin/neuromedin-B/ranatensin
390
NP01546 NP01552
Evidence 7 Activity

Activity

Neuropeptide

Target

Neuromedin-B receptor
Mus musculus

Source & Reference

NA
NeuroPepV2

Other

Mus musculus
Bombesin/neuromedin-B/ranatensin
390
NP01547 NP01553
Evidence 8 Activity

Activity

Neuropeptide

Source & Reference

NA
NeuroPepV2

Other

Sus scrofa
Bombesin/neuromedin-B/ranatensin
Additional Detail Fields 4 fields
Bombesin/neuromedin-B/ranatensin
Intravenous
390
NP01546 NP01552 NP01547 NP01553