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Peptide record

TPDB50537

Antifungal standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB50537
Antifungal
Anti-infective peptides
Peptipedia
standard
No
A 51-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QKLCQRPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
Physicochemical Analysis
C242H373N75O69S8
DM
C
5693.56
8.52
8
1
14
+5
5.68
-0.451
47.84
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8980
157.72
23
Residue Composition
number
3
A
2
R
6
N
0
D
8
C
1
E
3
Q
4
G
2
H
2
I
2
L
4
K
0
M
2
F
3
P
3
S
1
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 3 R: 2 N: 6 D: 0 C: 8 E: 1 Q: 3 G: 4 H: 2 I: 2 L: 2 K: 4 M: 0 F: 2 P: 3 S: 3 T: 1 W: 1 Y: 2 V: 2
Chemical Descriptors
51
C242H373N75O69S8
5693.56
8.52
+5
5.68
-0.451
Evidence Records 6 records
Evidence 1 Activity

Activity

IC50
Antifungal
4.5 µg/mL

Target

A. brassicola

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 4.5 ug/ml), B. cinerea (IC50 3.5 ug/ml), F. culmorum (IC50 2.3 ug/ml), F. oxysporum f.sp. lycopersic
Evidence 2 Activity

Activity

IC50
Antifungal
3.5 µg/mL

Target

B. cinerea

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 4.5 ug/ml), B. cinerea (IC50 3.5 ug/ml), F. culmorum (IC50 2.3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 2.3 ug/ml), P. oryzae
Evidence 3 Activity

Activity

IC50
Antifungal
2.3 µg/mL

Target

F. culmorum

Source & Reference

NA

Other

alt medium A: active against A. brassicola (IC50 4.5 ug/ml), B. cinerea (IC50 3.5 ug/ml), F. culmorum (IC50 2.3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 2.3 ug/ml), P. oryzae (IC50 0.3 ug/ml), and V. dahl
Evidence 4 Activity

Activity

IC50
Antifungal
2.3 µg/mL

Target

p. lycopersici

Source & Reference

NA

Other

50 4.5 ug/ml), B. cinerea (IC50 3.5 ug/ml), F. culmorum (IC50 2.3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 2.3 ug/ml), P. oryzae (IC50 0.3 ug/ml), and V. dahliae (IC50 1.2 ug/ml). Activity and Seq updated 2/
Evidence 5 Activity

Activity

IC50
Antifungal
0.3 µg/mL

Target

P. oryzae

Source & Reference

NA

Other

.5 ug/ml), F. culmorum (IC50 2.3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 2.3 ug/ml), P. oryzae (IC50 0.3 ug/ml), and V. dahliae (IC50 1.2 ug/ml). Activity and Seq updated 2/2023.
Evidence 6 Activity

Activity

IC50
Antifungal
1.2 µg/mL

Target

V. dahliae

Source & Reference

NA

Other

ug/ml), F. oxysporum f.sp. lycopersici (IC50 2.3 ug/ml), P. oryzae (IC50 0.3 ug/ml), and V. dahliae (IC50 1.2 ug/ml). Activity and Seq updated 2/2023.