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Peptide record

TPDB50536

Antifungal standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB50536
Antifungal
Anti-infective peptides
Peptipedia
standard
No
A 27-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QKLCERPSGTWSGVCGNNNACKNQCIR
Physicochemical Analysis
C119H196N42O39S4
DHMFY
NC
2967.36
8.73
4
1
5
+3
5.56
-0.852
43.33
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
5750
193.77
13
Residue Composition
number
1
A
2
R
4
N
0
D
4
C
1
E
2
Q
3
G
0
H
1
I
1
L
2
K
0
M
0
F
1
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 4 D: 0 C: 4 E: 1 Q: 2 G: 3 H: 0 I: 1 L: 1 K: 2 M: 0 F: 0 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C119H196N42O39S4
2967.36
8.73
+3
5.56
-0.852
Evidence Records 6 records
Evidence 1 Activity

Activity

IC50
Antifungal
75 µg/mL

Target

A. brassicola

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 75 ug/ml), B.cinerea (IC50 >100 ug/ml), F. culmorum (IC50 38 ug/ml), F. oxysporum f.sp. lycopersici
Evidence 2 Activity

Activity

IC50
Antifungal
>100 µg/mL

Target

B.cinerea

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 75 ug/ml), B.cinerea (IC50 >100 ug/ml), F. culmorum (IC50 38 ug/ml), F. oxysporum f.sp. lycopersici (IC50 42 ug/ml), P. oryzae (
Evidence 3 Activity

Activity

IC50
Antifungal
38 µg/mL

Target

F. culmorum

Source & Reference

NA

Other

salt medium A: active against A. brassicola (IC50 75 ug/ml), B.cinerea (IC50 >100 ug/ml), F. culmorum (IC50 38 ug/ml), F. oxysporum f.sp. lycopersici (IC50 42 ug/ml), P. oryzae (IC50 3 ug/ml), and V. dahliae
Evidence 4 Activity

Activity

IC50
Antifungal
42 µg/mL

Target

p. lycopersici

Source & Reference

NA

Other

IC50 75 ug/ml), B.cinerea (IC50 >100 ug/ml), F. culmorum (IC50 38 ug/ml), F. oxysporum f.sp. lycopersici (IC50 42 ug/ml), P. oryzae (IC50 3 ug/ml), and V. dahliae (IC50 15 ug/ml). Activity and Seq updated 2/202
Evidence 5 Activity

Activity

IC50
Antifungal
3 µg/mL

Target

P. oryzae

Source & Reference

NA

Other

>100 ug/ml), F. culmorum (IC50 38 ug/ml), F. oxysporum f.sp. lycopersici (IC50 42 ug/ml), P. oryzae (IC50 3 ug/ml), and V. dahliae (IC50 15 ug/ml). Activity and Seq updated 2/2023.
Evidence 6 Activity

Activity

IC50
Antifungal
15 µg/mL

Target

V. dahliae

Source & Reference

NA

Other

38 ug/ml), F. oxysporum f.sp. lycopersici (IC50 42 ug/ml), P. oryzae (IC50 3 ug/ml), and V. dahliae (IC50 15 ug/ml). Activity and Seq updated 2/2023.