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Peptide record

TPDB50535

Antifungal standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB50535
Antifungal
Anti-infective peptides
Peptipedia
standard
No
A 51-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QKLCERPSGTWSGVCGNNNACKNQCINLEGARHGSCNYVFPYHRCICYFPC
Physicochemical Analysis
C244H367N75O71S8
DM
C
5743.54
8.10
7
2
14
+3
5.19
-0.455
45.88
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
10470
182.29
23
Residue Composition
number
2
A
3
R
6
N
0
D
8
C
2
E
2
Q
5
G
2
H
2
I
2
L
2
K
0
M
2
F
3
P
3
S
1
T
1
W
3
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 6 D: 0 C: 8 E: 2 Q: 2 G: 5 H: 2 I: 2 L: 2 K: 2 M: 0 F: 2 P: 3 S: 3 T: 1 W: 1 Y: 3 V: 2
Chemical Descriptors
51
C244H367N75O71S8
5743.54
8.10
+3
5.19
-0.455
Evidence Records 6 records
Evidence 1 Activity

Activity

IC50
Antifungal
3 µg/mL

Target

A. brassicola

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 3 ug/ml), B. cinerea (IC50 1.5 ug/ml), F. culmorum (IC50 2 ug/ml), F. oxysporum f.sp. lycopersici
Evidence 2 Activity

Activity

IC50
Antifungal
1.5 µg/mL

Target

B. cinerea

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 3 ug/ml), B. cinerea (IC50 1.5 ug/ml), F. culmorum (IC50 2 ug/ml), F. oxysporum f.sp. lycopersici (IC50 1.8 ug/ml), P. oryzae (
Evidence 3 Activity

Activity

IC50
Antifungal
2 µg/mL

Target

F. culmorum

Source & Reference

NA

Other

salt medium A: active against A. brassicola (IC50 3 ug/ml), B. cinerea (IC50 1.5 ug/ml), F. culmorum (IC50 2 ug/ml), F. oxysporum f.sp. lycopersici (IC50 1.8 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dah
Evidence 4 Activity

Activity

IC50
Antifungal
1.8 µg/mL

Target

p. lycopersici

Source & Reference

NA

Other

(IC50 3 ug/ml), B. cinerea (IC50 1.5 ug/ml), F. culmorum (IC50 2 ug/ml), F. oxysporum f.sp. lycopersici (IC50 1.8 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 0.8 ug/ml). Activity and seq updated 2
Evidence 5 Activity

Activity

IC50
Antifungal
0.25 µg/mL

Target

P. oryzae

Source & Reference

NA

Other

1.5 ug/ml), F. culmorum (IC50 2 ug/ml), F. oxysporum f.sp. lycopersici (IC50 1.8 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 0.8 ug/ml). Activity and seq updated 2/2023.
Evidence 6 Activity

Activity

IC50
Antifungal
0.8 µg/mL

Target

V. dahliae

Source & Reference

NA

Other

ug/ml), F. oxysporum f.sp. lycopersici (IC50 1.8 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 0.8 ug/ml). Activity and seq updated 2/2023.