TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB50524

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 83-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

PLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

FASTA

>TPDB50524|Antifungal|length=83
PLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Formula C408H665N121O115S7

Absent Amino Acids W

Common Amino Acids K

Mass 9329.93

PI 9.85

Basic Residues 19

Acidic Residues 6

Hydrophobic Residues 24

Net Charge +9

Boman Index 24.25

Hydrophobicity -0.540

Aliphatic Index 65.66

Half Life

Mammalian: >20 hour Yeast: >20 hour E.coli: ?

Extinction Coefficient Cystines 3355

Absorbance 280nm 35.96

Polar Residues 25

number

3

A

5

R

1

N

2

D

6

C

4

E

4

Q

5

G

4

H

1

I

7

L

10

K

1

M

3

F

6

P

6

S

6

T

0

W

2

Y

7

V

Amino Acid Distribution

A: 3 R: 5 N: 1 D: 2 C: 6 E: 4 Q: 4 G: 5 H: 4 I: 1 L: 7 K: 10 M: 1 F: 3 P: 6 S: 6 T: 6 W: 0 Y: 2 V: 7

Length

83

Formula

C408H665N121O115S7

Mass

9329.93

PI

9.85

Net Charge

+9

Boman Index

24.25

Hydrophobicity

-0.540

Evidence 1 Activity

Source & Reference

Database Source NA