TPDB

3D PDB MODEL

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TPDB ID TPDB50450

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 94-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MSARCQITGRTVGFGKAVSHSHRRTRRRWPPNIQLKAYYLPSEDRRIKVRVSAQGIKVIDRDGHRGRRRAARAGSAPAHFARQAGSSLRTAAIL

FASTA

>TPDB50450|Antifungal|length=94
MSARCQITGRTVGFGKAVSHSHRRTRRRWPPNIQLKAYYLPSEDRRIKVRVSAQGIKVIDRDGHRGRRRAARAGSAPAHFARQAGSSLRTAAIL

Formula C452H754N166O122S2

Absent Amino Acids

Common Amino Acids R

Mass 10530.12

PI 12.50

Basic Residues 26

Acidic Residues 4

Hydrophobic Residues 34

Net Charge +18

Boman Index 21.89

Hydrophobicity -0.709

Aliphatic Index 70.74

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 8480

Absorbance 280nm 80.53

Polar Residues 20

number

13

A

18

R

1

N

3

D

1

C

1

E

4

Q

8

G

4

H

6

I

4

L

4

K

1

M

2

F

4

P

8

S

4

T

1

W

2

Y

5

V

Amino Acid Distribution

A: 13 R: 18 N: 1 D: 3 C: 1 E: 1 Q: 4 G: 8 H: 4 I: 6 L: 4 K: 4 M: 1 F: 2 P: 4 S: 8 T: 4 W: 1 Y: 2 V: 5

Length

94

Formula

C452H754N166O122S2

Mass

10530.12

PI

12.50

Net Charge

+18

Boman Index

21.89

Hydrophobicity

-0.709

Evidence 1 Activity

Source & Reference

Database Source NA