TPDB

3D PDB MODEL

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TPDB ID TPDB50422

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 94-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MPRRSIWKGSFVDAFLLRMKKKRDLLFNRKIWSRRSSILPEFVDCFVRIYNGKTFVRCKITEGKVGHKFGEFAFTRKRRPSRTNIGPGRKRGKK

FASTA

>TPDB50422|Antifungal|length=94
MPRRSIWKGSFVDAFLLRMKKKRDLLFNRKIWSRRSSILPEFVDCFVRIYNGKTFVRCKITEGKVGHKFGEFAFTRKRRPSRTNIGPGRKRGKK

Formula C508H823N159O121S4

Absent Amino Acids Q

Common Amino Acids R

Mass 11222.36

PI 12.14

Basic Residues 29

Acidic Residues 6

Hydrophobic Residues 32

Net Charge +22

Boman Index 19.81

Hydrophobicity -0.730

Aliphatic Index 63.19

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12615

Absorbance 280nm 112.41

Polar Residues 16

number

2

A

15

R

3

N

3

D

2

C

3

E

0

Q

8

G

1

H

6

I

5

L

13

K

2

M

9

F

4

P

6

S

4

T

2

W

1

Y

5

V

Amino Acid Distribution

A: 2 R: 15 N: 3 D: 3 C: 2 E: 3 Q: 0 G: 8 H: 1 I: 6 L: 5 K: 13 M: 2 F: 9 P: 4 S: 6 T: 4 W: 2 Y: 1 V: 5

Length

94

Formula

C508H823N159O121S4

Mass

11222.36

PI

12.14

Net Charge

+22

Boman Index

19.81

Hydrophobicity

-0.730

Evidence 1 Activity

Source & Reference

Database Source NA