TPDB

3D PDB MODEL

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TPDB ID TPDB50170

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 100-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

MAKKSMIERDKKRENLMNKYLVKRQQLKTRLNETDSVEEKLLLNQELQKLPRNSAPSRVRIRCWLTGRPRGNYRDFGVSRHVLREMAHQGLLPGVTKSSW

FASTA

>TPDB50170|Antifungal|length=100
MAKKSMIERDKKRENLMNKYLVKRQQLKTRLNETDSVEEKLLLNQELQKLPRNSAPSRVRIRCWLTGRPRGNYRDFGVSRHVLREMAHQGLLPGVTKSSW

Formula C514H860N166O145S5

Absent Amino Acids

Common Amino Acids RL

Mass 11845.81

PI 11.21

Basic Residues 25

Acidic Residues 10

Hydrophobic Residues 33

Net Charge +13

Boman Index 33.06

Hydrophobicity -0.967

Aliphatic Index 78.90

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 13980

Absorbance 280nm 118.02

Polar Residues 25

number

3

A

13

R

6

N

3

D

1

C

7

E

5

Q

5

G

2

H

2

I

13

L

10

K

4

M

1

F

4

P

7

S

4

T

2

W

2

Y

6

V

Amino Acid Distribution

A: 3 R: 13 N: 6 D: 3 C: 1 E: 7 Q: 5 G: 5 H: 2 I: 2 L: 13 K: 10 M: 4 F: 1 P: 4 S: 7 T: 4 W: 2 Y: 2 V: 6

Length

100

Formula

C514H860N166O145S5

Mass

11845.81

PI

11.21

Net Charge

+13

Boman Index

33.06

Hydrophobicity

-0.967

Evidence 1 Activity

Source & Reference

Database Source NA