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Peptide record

TPDB50090

DPV7 Antifungal Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB50090
DPV7
Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD CPPsite3.0
standard
No
A 15-aa standard natural multi-activity (Antifungal and Cell-penetrating Peptides) peptide sequence curated from Peptipedia, CellPPD, and CPPsite3.0, with an available 3D structural model.
N-terminal: Cys addition
Sequence
GKRKKKGKLGKKRDP
Physicochemical Analysis
C75H142N28O18
ANCEQHIMFSTWYV
K
1724.13
11.76
9
1
1
+8
9.70
-2.587
26.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
0
I
1
L
7
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 7 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C75H142N28O18
1724.13
11.76
+8
9.70
-2.587
Free
L
Linear
Cys addition
NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, HCT116, HL-60, K562, Molt4, NIH-3T3 and primary hepatocyte cultures

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Protein (PO and IgG)
Cytoplasm
Energy-dependent endocytic process involving cell membrane lipid rafts
In vitro
CCCCSSSSSBTTBCC
Additional Detail Fields 1 fields
CCCCSSSSSBTTBCC