Back to search

Peptide record

TPDB50083

Antifungal standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB50083
Antifungal
Anti-infective peptides
Peptipedia
standard
No
A 18-aa standard-residue antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GICRCFCRRGVCRCICLL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C84H148N30O19S6
ANDEQHKMPSTWY
C
2074.65
8.61
4
0
6
+4
1.30
1.100
102.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
375
0.18
6
Residue Composition
number
0
A
4
R
0
N
0
D
6
C
0
E
0
Q
2
G
0
H
2
I
2
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 6 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18 reviewed residue count
C84H148N30O19S6 sequence-only estimate (linear, free termini)
2074.65 sequence-only estimate (linear, free termini)
8.61 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
1.30 sequence-only estimate (linear, free termini)
1.100 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

MIC
Antifungal
12-25 µg/mL

Target

Candida albicans clinical isolates

Source & Reference

NA

Other

Active against drug resistant C. albicans clinical isolates (MIC 12-25 ug/ml). Updated seq8/2022