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Peptide record

TPDB50056

Antifungal standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB50056
Antifungal
Anti-infective peptides
Peptipedia
standard
No
A 20-aa standard natural antifungal peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
CHPTHTVATDDQGHLCTTII
Physicochemical Analysis
C90H143N27O31S2
RNEKMFSWY
T
2163.41
5.71
3
2
5
-2
5.32
-0.090
78.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
5.78
8
Residue Composition
number
1
A
0
R
0
N
2
D
2
C
0
E
1
Q
1
G
3
H
2
I
1
L
0
K
0
M
0
F
1
P
0
S
5
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 2 C: 2 E: 0 Q: 1 G: 1 H: 3 I: 2 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 5 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C90H143N27O31S2
2163.41
5.71
-2
5.32
-0.090
Evidence Records 15 records
Evidence 1 Activity

Activity

MIC
Antifungal
33.3 µg/mL

Target

M. diernhoferi DSM 43524

Source & Reference

NA

Other

using a 1:1 mixture of pinensins A and B. Active against E.coli DSM 1116 (no inhibition), M. diernhoferi DSM 43524 (MIC 33.3 ug/ml), Nocardia sp. DSM 43069(MIC 33.3 ug/ml), S.aureus DSM 346 (no inhibition), C. violaceum D
Evidence 2 Activity

Activity

MIC
Antifungal
33.3 µg/mL

Target

p. DSM 43069

Source & Reference

NA

Other

nst E.coli DSM 1116 (no inhibition), M. diernhoferi DSM 43524 (MIC 33.3 ug/ml), Nocardia sp. DSM 43069(MIC 33.3 ug/ml), S.aureus DSM 346 (no inhibition), C. violaceum DSM 30191 (MIC 67 ug/ml), D. hansenii DSM
Evidence 3 Activity

Activity

MIC
Antifungal
67 µg/mL

Target

C. violaceum DSM 30191

Source & Reference

NA

Other

IC 33.3 ug/ml), Nocardia sp. DSM 43069(MIC 33.3 ug/ml), S.aureus DSM 346 (no inhibition), C. violaceum DSM 30191 (MIC 67 ug/ml), D. hansenii DSM 3428 (MIC 33.3 ug/ml), P. membranifaciens DSM 21959 (MIC 4.2 ug/ml), R.
Evidence 4 Activity

Activity

MIC
Antifungal
33.3 µg/mL

Target

D. hansenii DSM 3428

Source & Reference

NA

Other

MIC 33.3 ug/ml), S.aureus DSM 346 (no inhibition), C. violaceum DSM 30191 (MIC 67 ug/ml), D. hansenii DSM 3428 (MIC 33.3 ug/ml), P. membranifaciens DSM 21959 (MIC 4.2 ug/ml), R. glutinis DSM 10134 (MIC 2.1 ug/ml), S.
Evidence 5 Activity

Activity

MIC
Antifungal
4.2 µg/mL

Target

P. membranifaciens DSM 21959

Source & Reference

NA

Other

nhibition), C. violaceum DSM 30191 (MIC 67 ug/ml), D. hansenii DSM 3428 (MIC 33.3 ug/ml), P. membranifaciens DSM 21959 (MIC 4.2 ug/ml), R. glutinis DSM 10134 (MIC 2.1 ug/ml), S. cerevisiae BT27c-3 A (MIC 2.1 ug/ml), A. clava
Evidence 6 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

R. glutinis DSM 10134

Source & Reference

NA

Other

ml), D. hansenii DSM 3428 (MIC 33.3 ug/ml), P. membranifaciens DSM 21959 (MIC 4.2 ug/ml), R. glutinis DSM 10134 (MIC 2.1 ug/ml), S. cerevisiae BT27c-3 A (MIC 2.1 ug/ml), A. clavatus DSM 816 (MIC 2.1 ug/ml), A. flavus
Evidence 7 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

S. cerevisiae BT27c-3 A

Source & Reference

NA

Other

ml), P. membranifaciens DSM 21959 (MIC 4.2 ug/ml), R. glutinis DSM 10134 (MIC 2.1 ug/ml), S. cerevisiae BT27c-3 A (MIC 2.1 ug/ml), A. clavatus DSM 816 (MIC 2.1 ug/ml), A. flavus DSM 1959* (MIC 4.2 ug/ml), A. fumigatus D
Evidence 8 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

A. clavatus DSM 816

Source & Reference

NA

Other

2 ug/ml), R. glutinis DSM 10134 (MIC 2.1 ug/ml), S. cerevisiae BT27c-3 A (MIC 2.1 ug/ml), A. clavatus DSM 816 (MIC 2.1 ug/ml), A. flavus DSM 1959* (MIC 4.2 ug/ml), A. fumigatus DSM 15966 (MIC 4.2 ug/ml), B. fuckelia
Evidence 9 Activity

Activity

MIC
Antifungal
4.2 µg/mL

Target

A. fumigatus DSM 15966

Source & Reference

NA

Other

MIC 2.1 ug/ml), A. clavatus DSM 816 (MIC 2.1 ug/ml), A. flavus DSM 1959* (MIC 4.2 ug/ml), A. fumigatus DSM 15966 (MIC 4.2 ug/ml), B. fuckeliana DSM 877 (MIC 4.2 ug/ml), E. floccosum DSM 10709 (MIC 16.6 ug/ml), H. resin
Evidence 10 Activity

Activity

MIC
Antifungal
4.2 µg/mL

Target

B. fuckeliana DSM 877

Source & Reference

NA

Other

2.1 ug/ml), A. flavus DSM 1959* (MIC 4.2 ug/ml), A. fumigatus DSM 15966 (MIC 4.2 ug/ml), B. fuckeliana DSM 877 (MIC 4.2 ug/ml), E. floccosum DSM 10709 (MIC 16.6 ug/ml), H. resinae DSM 1203 (MIC 2.1 ug/ml), M. hiemali
Evidence 11 Activity

Activity

MIC
Antifungal
16.6 µg/mL

Target

E. floccosum DSM 10709

Source & Reference

NA

Other

.2 ug/ml), A. fumigatus DSM 15966 (MIC 4.2 ug/ml), B. fuckeliana DSM 877 (MIC 4.2 ug/ml), E. floccosum DSM 10709 (MIC 16.6 ug/ml), H. resinae DSM 1203 (MIC 2.1 ug/ml), M. hiemalis DSM 2656 (MIC 2.1 ug/ml), P. capsulatum
Evidence 12 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

H. resinae DSM 1203

Source & Reference

NA

Other

2 ug/ml), B. fuckeliana DSM 877 (MIC 4.2 ug/ml), E. floccosum DSM 10709 (MIC 16.6 ug/ml), H. resinae DSM 1203 (MIC 2.1 ug/ml), M. hiemalis DSM 2656 (MIC 2.1 ug/ml), P. capsulatum DSM 2210 (MIC 2.1 ug/ml), and P. dre
Evidence 13 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

M. hiemalis DSM 2656

Source & Reference

NA

Other

4.2 ug/ml), E. floccosum DSM 10709 (MIC 16.6 ug/ml), H. resinae DSM 1203 (MIC 2.1 ug/ml), M. hiemalis DSM 2656 (MIC 2.1 ug/ml), P. capsulatum DSM 2210 (MIC 2.1 ug/ml), and P. drechsleri DSM 62679 (MIC 4.2 ug/ml).
Evidence 14 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

P. capsulatum DSM 2210

Source & Reference

NA

Other

C 16.6 ug/ml), H. resinae DSM 1203 (MIC 2.1 ug/ml), M. hiemalis DSM 2656 (MIC 2.1 ug/ml), P. capsulatum DSM 2210 (MIC 2.1 ug/ml), and P. drechsleri DSM 62679 (MIC 4.2 ug/ml).
Evidence 15 Activity

Activity

MIC
Antifungal
4.2 µg/mL

Target

P. drechsleri DSM 62679

Source & Reference

NA

Other

ug/ml), M. hiemalis DSM 2656 (MIC 2.1 ug/ml), P. capsulatum DSM 2210 (MIC 2.1 ug/ml), and P. drechsleri DSM 62679 (MIC 4.2 ug/ml).