TPDB

3D PDB MODEL

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TPDB ID TPDB49951

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 143-aa standard natural antifungal peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

PAGPFGIPKCRKEFQQAQHLRACQQWLHKQAMQSGSGPSLALYGEFEDDMENPQGPQQRPPLLQQCCNELHQEEPLCVCPTLKGASKAVKQQVRQQLGQQGQQGPQVQHVISRIYQTATHLPKVCNIPQVSVCPFKKTMPGPS

FASTA

>TPDB49951|Antifungal|length=143
PAGPFGIPKCRKEFQQAQHLRACQQWLHKQAMQSGSGPSLALYGEFEDDMENPQGPQQRPPLLQQCCNELHQEEPLCVCPTLKGASKAVKQQVRQQLGQQGQQGPQVQHVISRIYQTATHLPKVCNIPQVSVCPFKKTMPGPS

Formula C691H1098N206O203S11

Absent Amino Acids

Common Amino Acids Q

Mass 15892.24

PI 8.51

Basic Residues 19

Acidic Residues 9

Hydrophobic Residues 41

Net Charge +5

Boman Index 39.84

Hydrophobicity -0.701

Aliphatic Index 62.73

Half Life

Mammalian: >20 hour Yeast: >20 hour E.coli: ?

Extinction Coefficient Cystines 8980

Absorbance 280nm 56.51

Polar Residues 49

number

8

A

5

R

3

N

2

D

8

C

7

E

25

Q

11

G

5

H

4

I

11

L

9

K

3

M

4

F

16

P

7

S

4

T

1

W

2

Y

8

V

Amino Acid Distribution

A: 8 R: 5 N: 3 D: 2 C: 8 E: 7 Q: 25 G: 11 H: 5 I: 4 L: 11 K: 9 M: 3 F: 4 P: 16 S: 7 T: 4 W: 1 Y: 2 V: 8

Length

143

Formula

C691H1098N206O203S11

Mass

15892.24

PI

8.51

Net Charge

+5

Boman Index

39.84

Hydrophobicity

-0.701

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.