TPDB

3D PDB MODEL

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TPDB ID TPDB49933

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 164-aa standard natural antifungal peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MLSTKQLVILGLLGCLSTLQAGVVLNVNPGKSLEEPAVKHLKVSPVNANEVPVLKELKSVQKTKSGDTLYGFVCTVGQIKTDSLGCVGSDSVAWPSEQNVELTVSCDKSNVGRIITYVEVHFVVSTQNVGCNVSAGSIGTSSIEVKVYAAGTNYLEYSSLFYIQ

FASTA

>TPDB49933|Antifungal|length=164
MLSTKQLVILGLLGCLSTLQAGVVLNVNPGKSLEEPAVKHLKVSPVNANEVPVLKELKSVQKTKSGDTLYGFVCTVGQIKTDSLGCVGSDSVAWPSEQNVELTVSCDKSNVGRIITYVEVHFVVSTQNVGCNVSAGSIGTSSIEVKVYAAGTNYLEYSSLFYIQ

Formula C772H1251N199O243S6

Absent Amino Acids

Common Amino Acids V

Mass 17400.97

PI 6.10

Basic Residues 14

Acidic Residues 13

Hydrophobic Residues 67

Net Charge -1

Boman Index 27.52

Hydrophobicity 0.220

Aliphatic Index 105.55

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 14690

Absorbance 280nm 84.42

Polar Residues 57

number

7

A

1

R

9

N

4

D

5

C

9

E

7

Q

14

G

2

H

7

I

17

L

11

K

1

M

3

F

5

P

19

S

11

T

1

W

6

Y

25

V

Amino Acid Distribution

A: 7 R: 1 N: 9 D: 4 C: 5 E: 9 Q: 7 G: 14 H: 2 I: 7 L: 17 K: 11 M: 1 F: 3 P: 5 S: 19 T: 11 W: 1 Y: 6 V: 25

Length

164

Formula

C772H1251N199O243S6

Mass

17400.97

PI

6.10

Net Charge

-1

Boman Index

27.52

Hydrophobicity

0.220

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.