TPDB

3D PDB MODEL

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TPDB ID TPDB49857

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 40-aa standard natural antifungal peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

QDNSRYTHFLTQHYDAKPQGRDDRYSESIMRRRGLTSPSK

FASTA

>TPDB49857|Antifungal|length=40
QDNSRYTHFLTQHYDAKPQGRDDRYSESIMRRRGLTSPSK

Formula C203H318N68O66S1

Absent Amino Acids CWV

Common Amino Acids R

Mass 4799.23

PI 10.14

Basic Residues 10

Acidic Residues 5

Hydrophobic Residues 9

Net Charge +3

Boman Index 14.07

Hydrophobicity -1.703

Aliphatic Index 31.75

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 4470

Absorbance 280nm 93.14

Polar Residues 15

number

1

A

6

R

1

N

4

D

0

C

1

E

3

Q

2

G

2

H

1

I

2

L

2

K

1

M

1

F

2

P

5

S

3

T

0

W

3

Y

0

V

Amino Acid Distribution

A: 1 R: 6 N: 1 D: 4 C: 0 E: 1 Q: 3 G: 2 H: 2 I: 1 L: 2 K: 2 M: 1 F: 1 P: 2 S: 5 T: 3 W: 0 Y: 3 V: 0

Length

40

Formula

C203H318N68O66S1

Mass

4799.23

PI

10.14

Net Charge

+3

Boman Index

14.07

Hydrophobicity

-1.703

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.