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Peptide record

TPDB49852

Antifungal standard
237 amino acids
Basic Information
3D PDB MODEL
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TPDB49852
Antifungal
Anti-infective peptides
dbAMP
standard
No
A 237-aa standard-residue antifungal peptide sequence curated from dbAMP, with an available 3D structural model.
Sequence
MAHYTTLLLSTLLVGTALAQRGSHHHHHHTKCMGPKDCLYPNPDSCTTYIQCVPLDEVGNAKPVVKPCPKGLQWNDNVGKKWCDYPNLSTCPVTTTRAPTTTTKSAPTVTTTTRAPTTTTPATKCMGPKDCLYPNPDSCTTYIQCVPLDEVGNAKPVVKPCPKGLQWNDNVGKKWCDYPNLSTCPVEAAAKEAAAKEAAAKEAAAKAMWKDVLKKIGTVALHAGKAALGAVADTISQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1107H1766N306O335S18
F
T
25299.13
8.41
34
18
82
+8
1.21
-0.347
67.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
38805
1.53
75
Residue Composition
number
28
A
3
R
10
N
12
D
14
C
6
E
6
Q
13
G
8
H
4
I
17
L
23
K
4
M
0
F
22
P
8
S
30
T
5
W
7
Y
17
V
Amino Acid Distribution
A: 28 R: 3 N: 10 D: 12 C: 14 E: 6 Q: 6 G: 13 H: 8 I: 4 L: 17 K: 23 M: 4 F: 0 P: 22 S: 8 T: 30 W: 5 Y: 7 V: 17
Chemical Descriptors
237 reviewed residue count
C1107H1766N306O335S18 sequence-only estimate (linear, free termini)
25299.13 sequence-only estimate (linear, free termini)
8.41 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
1.21 sequence-only estimate (linear, free termini)
-0.347 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.