Peptide record

TPDB49832

Antifungal standard
449 amino acids
Basic Information
3D PDB MODEL
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TPDB49832
Antifungal
Anti-infective peptides
dbAMP
standard
No
A 449-aa standard-residue antifungal peptide sequence curated from dbAMP, with an available 3D structural model.
Sequence
MRSAAVLALLLCAGQVIALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSKECFETLRGDERILSILRHQNLLKELQDLALQGAKERTHQQKKHSSYEDELSEVLEKPNDQAEPKEVTEEVSSKDAAEKRDDFKEVEKSDEDSDGDRPQASPGLGPGPKVEEDNQAPGEEEEAPSNAHPLASLPSPKYPGPQAKEDSEGPSQGPASREKGLSAEQGRQTEREEEEEKWEEAEAREKAVPEEESPPTAAFKPPPSLGNKETQRAAPGWPEDGAGKMGAEEAKPPEGKGEWAHSRQEEEEMARAPQVLFRGGKSGEPEQEEQLSKEWEDAKRWSKMDQLAKELTAEKRLEGEEEEEEDPDRSMRLSFRARGYGFRGPGLQLRRGWRPNSREDSVEAGLPLQVRGYPEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHQLEELRRG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C2136H3404N626O738S11
E
50014.94
4.51
71
104
123
-38
2.95
-1.202
56.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
39085
0.78
83
Residue Composition
number
40
A
31
R
9
N
22
D
3
C
82
E
23
Q
34
G
6
H
6
I
36
L
34
K
8
M
6
F
38
P
35
S
9
T
6
W
4
Y
17
V
Amino Acid Distribution
A: 40 R: 31 N: 9 D: 22 C: 3 E: 82 Q: 23 G: 34 H: 6 I: 6 L: 36 K: 34 M: 8 F: 6 P: 38 S: 35 T: 9 W: 6 Y: 4 V: 17
Chemical Descriptors
449 reviewed residue count
C2136H3404N626O738S11 sequence-only estimate (linear, free termini)
50014.94 sequence-only estimate (linear, free termini)
4.51 sequence-only estimate (linear, free termini)
-38 sequence-only estimate (linear, free termini)
2.95 sequence-only estimate (linear, free termini)
-1.202 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.