TPDB

3D PDB MODEL

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TPDB ID TPDB49830

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 282-aa standard natural antifungal peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

GSAAKMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVAAASGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK

FASTA

>TPDB49830|Antifungal|length=282
GSAAKMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVAAASGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK

Formula C1344H2141N373O385S4

Absent Amino Acids C

Common Amino Acids A

Mass 29813.29

PI 10.29

Basic Residues 37

Acidic Residues 20

Hydrophobic Residues 121

Net Charge +12

Boman Index 41.89

Hydrophobicity -0.083

Aliphatic Index 87.27

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 27960

Absorbance 280nm 93.78

Polar Residues 62

number

38

A

11

R

12

N

11

D

0

C

9

E

10

Q

26

G

6

H

8

I

29

L

20

K

4

M

12

F

20

P

15

S

21

T

4

W

4

Y

22

V

Amino Acid Distribution

A: 38 R: 11 N: 12 D: 11 C: 0 E: 9 Q: 10 G: 26 H: 6 I: 8 L: 29 K: 20 M: 4 F: 12 P: 20 S: 15 T: 21 W: 4 Y: 4 V: 22

Length

282

Formula

C1344H2141N373O385S4

Mass

29813.29

PI

10.29

Net Charge

+12

Boman Index

41.89

Hydrophobicity

-0.083

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.