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Peptide record

TPDB49826

Antifungal standard
165 amino acids
Basic Information
3D PDB MODEL
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TPDB49826
Antifungal
Anti-infective peptides
dbAMP PEPlife
standard
No
A 165-aa standard natural antifungal peptide sequence curated from dbAMP and PEPlife, with an available 3D structural model.
Sequence
CDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE
Physicochemical Analysis
C860H1353N227O255S9
L
19241.11
5.91
23
22
66
-2
36.42
-0.336
85.70
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
18700
97.19
49
Residue Composition
number
8
A
9
R
4
N
8
D
4
C
14
E
12
Q
5
G
3
H
8
I
21
L
11
K
5
M
10
F
5
P
14
S
10
T
2
W
5
Y
7
V
Amino Acid Distribution
A: 8 R: 9 N: 4 D: 8 C: 4 E: 14 Q: 12 G: 5 H: 3 I: 8 L: 21 K: 11 M: 5 F: 10 P: 5 S: 14 T: 10 W: 2 Y: 5 V: 7
Chemical Descriptors
165
C860H1353N227O255S9
19241.11
5.91
-2
36.42
-0.336
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Additional Detail Fields 6 fields
Half-life for IV infusion is 3.7 hours to 8.5 hours (mean 5.1 hours). IM half-life of interferon alfa-2a is 6 hours to 8 hours 10 hours (Escherichia coli, in vivo) 1.2 hours (mammalian reticulocytes, in vitro) 20 hours (yeast, in vivo)
21960.0 25200.0 36000.0 4320.0 72000.0
hours
-0.336
19241.1
5.99