TPDB

3D PDB MODEL

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TPDB ID TPDB49825

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 206-aa standard natural antifungal peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

AVFTVVNQCPFTVWAASVPVGGGRQLNRGESWRITAPAGTTAARIWARTGCKFDASGRGSCRTGDCGGVLQCTGYGRAPNTLAEYALKQFNNLDFFDISLIDGFNVPMSFLPDGGSGCSRGPRCAVDVNARCPAELRQDGVCNNACPVFKKDEYCCVGSAANDCHPTNYSRYFKGQCPDAYSYPKDDATSTFTCPAGTNYKVVFCP

FASTA

>TPDB49825|Antifungal|length=206
AVFTVVNQCPFTVWAASVPVGGGRQLNRGESWRITAPAGTTAARIWARTGCKFDASGRGSCRTGDCGGVLQCTGYGRAPNTLAEYALKQFNNLDFFDISLIDGFNVPMSFLPDGGSGCSRGPRCAVDVNARCPAELRQDGVCNNACPVFKKDEYCCVGSAANDCHPTNYSRYFKGQCPDAYSYPKDDATSTFTCPAGTNYKVVFCP

Formula C958H1455N275O293S17

Absent Amino Acids

Common Amino Acids G

Mass 22057.78

PI 7.69

Basic Residues 21

Acidic Residues 17

Hydrophobic Residues 72

Net Charge +2

Boman Index 22.11

Hydrophobicity -0.245

Aliphatic Index 54.03

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 29420

Absorbance 280nm 133.38

Polar Residues 68

number

21

A

13

R

12

N

13

D

16

C

4

E

6

Q

22

G

1

H

4

I

8

L

7

K

1

M

12

F

14

P

12

S

14

T

3

W

8

Y

15

V

Amino Acid Distribution

A: 21 R: 13 N: 12 D: 13 C: 16 E: 4 Q: 6 G: 22 H: 1 I: 4 L: 8 K: 7 M: 1 F: 12 P: 14 S: 12 T: 14 W: 3 Y: 8 V: 15

Length

206

Formula

C958H1455N275O293S17

Mass

22057.78

PI

7.69

Net Charge

+2

Boman Index

22.11

Hydrophobicity

-0.245

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.