TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB49823

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 205-aa standard natural antifungal peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

ATIEVRNNCPYTVWAASTPIGGGRRLDRGQTWVINAPRGTKMARVWGRTNCNFNAAGRGTCQTGDCGGVLQCTGWGKPPNTLAEYALDQFSGLDFWDISLVDGFNIPMTFAPTNPSGGKCHAIHCTANINGECPRELRVPGGCNNPCTTFGGQQYCCTQGPCGPTFFSKFFKQRCPDAYSYPQDDPTSTFTCPGGSTNYRVIFCP

FASTA

>TPDB49823|Antifungal|length=205
ATIEVRNNCPYTVWAASTPIGGGRRLDRGQTWVINAPRGTKMARVWGRTNCNFNAAGRGTCQTGDCGGVLQCTGWGKPPNTLAEYALDQFSGLDFWDISLVDGFNIPMTFAPTNPSGGKCHAIHCTANINGECPRELRVPGGCNNPCTTFGGQQYCCTQGPCGPTFFSKFFKQRCPDAYSYPQDDPTSTFTCPGGSTNYRVIFCP

Formula C965H1452N278O290S18

Absent Amino Acids

Common Amino Acids G

Mass 22164.91

PI 7.85

Basic Residues 19

Acidic Residues 13

Hydrophobic Residues 61

Net Charge +3

Boman Index 18.38

Hydrophobicity -0.398

Aliphatic Index 46.20

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 37440

Absorbance 280nm 168.92

Polar Residues 74

number

13

A

12

R

14

N

9

D

16

C

4

E

9

Q

26

G

2

H

8

I

7

L

5

K

2

M

12

F

18

P

8

S

21

T

5

W

6

Y

8

V

Amino Acid Distribution

A: 13 R: 12 N: 14 D: 9 C: 16 E: 4 Q: 9 G: 26 H: 2 I: 8 L: 7 K: 5 M: 2 F: 12 P: 18 S: 8 T: 21 W: 5 Y: 6 V: 8

Length

205

Formula

C965H1452N278O290S18

Mass

22164.91

PI

7.85

Net Charge

+3

Boman Index

18.38

Hydrophobicity

-0.398

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.