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Peptide record

TPDB49821

Antifungal standard
254 amino acids
Basic Information
3D PDB MODEL
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TPDB49821
Antifungal
Anti-infective peptides
dbAMP
standard
No
A 254-aa standard-residue antifungal peptide sequence curated from dbAMP, with an available 3D structural model.
Sequence
ATAYTLNLANPSASQYSSFLDQIRNNVRDTSLIYGGTDVEVIGAPSTTDKFLRLNFQGPRGTVSLGLRRENLYVVAYLAMDNANVNRAYYFKNQITSAELTALFPEVVVANQKQLEYGEDYQAIEKNAKITTGDQSRKELGLGINLLITMIDGVNKKVRVVKDEARFLLIAIQMTAEAARFRYIQNLVTKNFPNKFDSENKVIQFQVSWSKISTAIFGDCKNGVFNKDYDFGFGKVRQAKDLQMGLLKYLGRPK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1282H2030N350O379S5
H
L
28570.64
9.73
33
25
110
+8
1.69
-0.283
89.84
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
23380
0.82
75
Residue Composition
number
21
A
14
R
20
N
14
D
1
C
11
E
14
Q
17
G
0
H
15
I
24
L
19
K
4
M
14
F
6
P
13
S
15
T
1
W
12
Y
19
V
Amino Acid Distribution
A: 21 R: 14 N: 20 D: 14 C: 1 E: 11 Q: 14 G: 17 H: 0 I: 15 L: 24 K: 19 M: 4 F: 14 P: 6 S: 13 T: 15 W: 1 Y: 12 V: 19
Chemical Descriptors
254 reviewed residue count
C1282H2030N350O379S5 sequence-only estimate (linear, free termini)
28570.64 sequence-only estimate (linear, free termini)
9.73 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
1.69 sequence-only estimate (linear, free termini)
-0.283 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.