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Peptide record

TPDB49818

Antifungal standard
266 amino acids
Basic Information
3D PDB MODEL
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TPDB49818
Antifungal
Anti-infective peptides
dbAMP
standard
No
A 266-aa standard-residue antifungal peptide sequence curated from dbAMP, with an available 3D structural model.
Sequence
APTLEINTITFDVGNATINKYATFMKSIHNQAKDPTLKCYGIPMLPNTNLTPKYLLVTLQDSSLKTITLMLKRNNLYVMGYADTYNGKCRYHIFKDISNTTERNDVMTTLCPNPSSRVGKNINYDSSYPALEKKVGRPRSQVQLGIQILNSGIGKIYGVDSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFYPNAKVLNLEESWGKISTAIHNAKNGALTSPLELKNANGSKWIVLRVDDIEPDVGLLKYVNGTCQAT
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1326H2114N356O398S10
NL
29732.12
9.41
34
23
106
+8
1.50
-0.311
88.35
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
30620
1.03
89
Residue Composition
number
17
A
9
R
25
N
11
D
4
C
12
E
8
Q
15
G
3
H
19
I
25
L
22
K
6
M
8
F
12
P
16
S
23
T
2
W
13
Y
16
V
Amino Acid Distribution
A: 17 R: 9 N: 25 D: 11 C: 4 E: 12 Q: 8 G: 15 H: 3 I: 19 L: 25 K: 22 M: 6 F: 8 P: 12 S: 16 T: 23 W: 2 Y: 13 V: 16
Chemical Descriptors
266 reviewed residue count
C1326H2114N356O398S10 sequence-only estimate (linear, free termini)
29732.12 sequence-only estimate (linear, free termini)
9.41 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
1.50 sequence-only estimate (linear, free termini)
-0.311 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.