TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB49816

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 69-aa standard natural antifungal peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.

Sequence

APMGSDPPTACCASYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN

FASTA

>TPDB49816|Antifungal|length=69
APMGSDPPTACCASYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN

Formula C340H518N88O109S5

Absent Amino Acids HI

Common Amino Acids S

Mass 7742.68

PI 4.56

Basic Residues 6

Acidic Residues 8

Hydrophobic Residues 26

Net Charge -2

Boman Index 13.10

Hydrophobicity -0.404

Aliphatic Index 60.72

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 13200

Absorbance 280nm 170.48

Polar Residues 27

number

6

A

3

R

2

N

4

D

4

C

4

E

4

Q

1

G

0

H

0

I

4

L

3

K

1

M

2

F

6

P

8

S

4

T

1

W

5

Y

7

V

Amino Acid Distribution

A: 6 R: 3 N: 2 D: 4 C: 4 E: 4 Q: 4 G: 1 H: 0 I: 0 L: 4 K: 3 M: 1 F: 2 P: 6 S: 8 T: 4 W: 1 Y: 5 V: 7

Length

69

Formula

C340H518N88O109S5

Mass

7742.68

PI

4.56

Net Charge

-2

Boman Index

13.10

Hydrophobicity

-0.404

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.