TPDB

3D PDB MODEL

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TPDB ID TPDB49562

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 35-aa modified antifungal peptide sequence curated from CAFPdb, DRAMP, dbAMP, and other sources, with an available 3D structural model.

Modification

Modified, details unspecified

Sequence

ACGGGGGDVGSLISASLFDQMLKYRNDPRCCXXGF

FASTA

>TPDB49562|Antifungal|length=35
ACGGGGGDVGSLISASLFDQMLKYRNDPRCCXXGF

Formula C143H224N42O46S4

Absent Amino Acids EHTW

Common Amino Acids G

Mass 3395.85

PI 6.09

Basic Residues 3

Acidic Residues 3

Hydrophobic Residues 11

Net Charge -0

Boman Index 1.80

Hydrophobicity 0.006

Aliphatic Index 58.57

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1615

Absorbance 280nm 47.56

Polar Residues 9

number

2

A

2

R

1

N

3

D

3

C

0

E

1

Q

7

G

0

H

1

I

3

L

1

K

1

M

2

F

1

P

3

S

0

T

0

W

1

Y

1

V

Amino Acid Distribution

A: 2 R: 2 N: 1 D: 3 C: 3 E: 0 Q: 1 G: 7 H: 0 I: 1 L: 3 K: 1 M: 1 F: 2 P: 1 S: 3 T: 0 W: 0 Y: 1 V: 1

Length

35

Formula

C143H224N42O46S4

Mass

3395.85

PI

6.09

Net Charge

-0

Boman Index

1.80

Hydrophobicity

0.006

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.