TPDB

3D PDB MODEL

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TPDB ID TPDB49557

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

CAFPdb dbAMP Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 37-aa modified antifungal peptide sequence curated from CAFPdb, dbAMP, and Peptipedia, with an available 3D structural model.

Modification

Modified, details unspecified

Sequence

ARFDIQNKCPYTVWAASVPVGGGRQLNSGQTWXIDAP

FASTA

>TPDB49557|Antifungal|length=37
ARFDIQNKCPYTVWAASVPVGGGRQLNSGQTWXIDAP

Formula C174H264N50O51S1

Absent Amino Acids EHM

Common Amino Acids AG

Mass 3904.37

PI 8.88

Basic Residues 3

Acidic Residues 2

Hydrophobic Residues 14

Net Charge +1

Boman Index 1.92

Hydrophobicity -0.324

Aliphatic Index 65.95

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12490

Absorbance 280nm 319.90

Polar Residues 11

number

4

A

2

R

2

N

2

D

1

C

0

E

3

Q

4

G

0

H

2

I

1

L

1

K

0

M

1

F

3

P

2

S

2

T

2

W

1

Y

3

V

Amino Acid Distribution

A: 4 R: 2 N: 2 D: 2 C: 1 E: 0 Q: 3 G: 4 H: 0 I: 2 L: 1 K: 1 M: 0 F: 1 P: 3 S: 2 T: 2 W: 2 Y: 1 V: 3

Length

37

Formula

C174H264N50O51S1

Mass

3904.37

PI

8.88

Net Charge

+1

Boman Index

1.92

Hydrophobicity

-0.324

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.