Peptide record

TPDB49553

Antifungal standard
245 amino acids
Basic Information
3D PDB MODEL
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TPDB49553
Antifungal
Anti-infective peptides
CAFPdb dbAMP
standard
No
A 245-aa standard-residue antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.
Sequence
MMKTLGAVLSLSLTILSFGGAHAAKMSFKNNCPYTVWPATQTSGKKPQLSTTGFKLAPHARFKLHTPVPWNGRFWARTGCSMDAYGKFVCATADCASGQVKCNGNGPIPPTTLAEFNIPAGGGKDFYDVSLVDGFNLPMSVNPQGGTGDCKTASCPKNVNKVCPRELQKKGANGKVVACLSACVAFQKPKYCCTPPQNTPETCPPTNYSQIFSHACPKAYSYAYDDKKGTFTCKGGPNYLITFCP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1162H1792N312O335S21
GP
26166.16
9.03
30
11
84
+15
1.02
-0.259
54.61
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
30910
1.18
83
Residue Composition
number
22
A
4
R
14
N
8
D
16
C
3
E
8
Q
23
G
4
H
5
I
14
L
22
K
5
M
13
F
23
P
15
S
21
T
3
W
9
Y
13
V
Amino Acid Distribution
A: 22 R: 4 N: 14 D: 8 C: 16 E: 3 Q: 8 G: 23 H: 4 I: 5 L: 14 K: 22 M: 5 F: 13 P: 23 S: 15 T: 21 W: 3 Y: 9 V: 13
Chemical Descriptors
245 reviewed residue count
C1162H1792N312O335S21 sequence-only estimate (linear, free termini)
26166.16 sequence-only estimate (linear, free termini)
9.03 sequence-only estimate (linear, free termini)
+15 sequence-only estimate (linear, free termini)
1.02 sequence-only estimate (linear, free termini)
-0.259 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.