TPDB

3D PDB MODEL

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TPDB ID TPDB49549

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

CAFPdb dbAMP

Sequence_Type

standard

Has_Modification No

Description A 255-aa standard natural antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.

Sequence

EQCGRQAGGALCPNGLCCSEFGWCGNTEPYCKQPGCQSQCTPGGTPPGPTGDLSGIISSSQFDDMLKHRNDAACPARGFYTYNAFITAAKSFPGFGTTGDTATRKKEVAAFFGQTSHETTGGWATAPDGPYSWGYCFKQEQNPASDYCEPSATWPCASGKRYYGRGPMQLSWNYNYGLCGRAIGVDLLNNPDLVANDAVIAFKAAIWFWMTAQPPKPSCHAVIAGQWQPSDADRAAGRLPGYGVITNIINGGLEC

FASTA

>TPDB49549|Antifungal|length=255
EQCGRQAGGALCPNGLCCSEFGWCGNTEPYCKQPGCQSQCTPGGTPPGPTGDLSGIISSSQFDDMLKHRNDAACPARGFYTYNAFITAAKSFPGFGTTGDTATRKKEVAAFFGQTSHETTGGWATAPDGPYSWGYCFKQEQNPASDYCEPSATWPCASGKRYYGRGPMQLSWNYNYGLCGRAIGVDLLNNPDLVANDAVIAFKAAIWFWMTAQPPKPSCHAVIAGQWQPSDADRAAGRLPGYGVITNIINGGLEC

Formula C1197H1776N330O364S18

Absent Amino Acids

Common Amino Acids G

Mass 27190.34

PI 5.86

Basic Residues 21

Acidic Residues 20

Hydrophobic Residues 88

Net Charge -2

Boman Index 21.23

Hydrophobicity -0.386

Aliphatic Index 49.92

Half Life

Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 61265

Absorbance 280nm 225.32

Polar Residues 83

number

28

A

9

R

12

N

12

D

15

C

8

E

13

Q

33

G

3

H

10

I

11

L

9

K

3

M

11

F

21

P

15

S

17

T

8

W

11

Y

6

V

Amino Acid Distribution

A: 28 R: 9 N: 12 D: 12 C: 15 E: 8 Q: 13 G: 33 H: 3 I: 10 L: 11 K: 9 M: 3 F: 11 P: 21 S: 15 T: 17 W: 8 Y: 11 V: 6

Length

255

Formula

C1197H1776N330O364S18

Mass

27190.34

PI

5.86

Net Charge

-2

Boman Index

21.23

Hydrophobicity

-0.386

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.