Peptide record

TPDB49548

Antifungal standard
255 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB49548
Antifungal
Anti-infective peptides
CAFPdb dbAMP
standard
No
A 255-aa standard-residue antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.
Sequence
EQCGSQAGGATCPNCLCCSRFGWCGSTSDYCGDGCQSQCAGCGGGGTPVTPTPTPSGGGGVSSIVSRALFDRMLLHRNDGACQAKGFYTYDAFVAAAGAFPGFGTTGSTDTRKREVAAFLAQTSHETTGGWATAPDGAFAWGYCFKQERGATSNYCTPSAQWPCAPGKSYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTAMWFWMTAQAPKPSSHAVITGQWSPSGTDRAAGRVPGFGVITN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1153H1726N330O357S17
G
26467.41
7.77
22
15
86
+3
1.22
-0.272
45.69
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
52785
1.99
85
Residue Composition
number
30
A
12
R
7
N
11
D
14
C
4
E
11
Q
38
G
4
H
5
I
9
L
6
K
3
M
12
F
18
P
20
S
24
T
7
W
9
Y
11
V
Amino Acid Distribution
A: 30 R: 12 N: 7 D: 11 C: 14 E: 4 Q: 11 G: 38 H: 4 I: 5 L: 9 K: 6 M: 3 F: 12 P: 18 S: 20 T: 24 W: 7 Y: 9 V: 11
Chemical Descriptors
255 reviewed residue count
C1153H1726N330O357S17 sequence-only estimate (linear, free termini)
26467.41 sequence-only estimate (linear, free termini)
7.77 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.22 sequence-only estimate (linear, free termini)
-0.272 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.