TPDB

3D PDB MODEL

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TPDB ID TPDB49544

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

CAFPdb dbAMP

Sequence_Type

standard

Has_Modification No

Description A 200-aa standard natural antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.

Sequence

VSSVISSSLFEKMLLHRGFYTYDAFIAAAKSFPAFATTGSTDVRKREVAAFLAQTSHETTGGWPTAPDGPYELGSTSDYFGRGPIQISYNYNYGAAGKAIGVDLLRNPDLVTSDNTVEFKTALWFWMTPQSPKPSSHDVITGRWSPSSTDKAAGRVPGYGVLTNIIDGGVECGKGQESHVADRIGYYKDNLDCYNQKPFA

FASTA

>TPDB49544|Antifungal|length=200
VSSVISSSLFEKMLLHRGFYTYDAFIAAAKSFPAFATTGSTDVRKREVAAFLAQTSHETTGGWPTAPDGPYELGSTSDYFGRGPIQISYNYNYGAAGKAIGVDLLRNPDLVTSDNTVEFKTALWFWMTPQSPKPSSHDVITGRWSPSSTDKAAGRVPGYGVLTNIIDGGVECGKGQESHVADRIGYYKDNLDCYNQKPFA

Formula C976H1468N258O299S4

Absent Amino Acids

Common Amino Acids G

Mass 21728.18

PI 6.07

Basic Residues 22

Acidic Residues 20

Hydrophobic Residues 77

Net Charge -2

Boman Index 25.35

Hydrophobicity -0.347

Aliphatic Index 65.40

Half Life

Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 38515

Absorbance 280nm 177.26

Polar Residues 60

number

18

A

8

R

7

N

13

D

2

C

7

E

5

Q

20

G

4

H

9

I

11

L

10

K

2

M

10

F

12

P

19

S

16

T

4

W

11

Y

12

V

Amino Acid Distribution

A: 18 R: 8 N: 7 D: 13 C: 2 E: 7 Q: 5 G: 20 H: 4 I: 9 L: 11 K: 10 M: 2 F: 10 P: 12 S: 19 T: 16 W: 4 Y: 11 V: 12

Length

200

Formula

C976H1468N258O299S4

Mass

21728.18

PI

6.07

Net Charge

-2

Boman Index

25.35

Hydrophobicity

-0.347

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.