TPDB

3D PDB MODEL

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TPDB ID TPDB49542

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 30-aa modified antifungal peptide sequence curated from CAFPdb, DRAMP, dbAMP, and other sources, with an available 3D structural model.

Modification

Modified, details unspecified

Sequence

ATFDIQNKXTYTVWAAAWAPSYPGGXKQLD

FASTA

>TPDB49542|Antifungal|length=30
ATFDIQNKXTYTVWAAAWAPSYPGGXKQLD

Formula C144H207N35O42

Absent Amino Acids RCEHM

Common Amino Acids A

Mass 3100.44

PI 6.76

Basic Residues 2

Acidic Residues 2

Hydrophobic Residues 13

Net Charge -0

Boman Index -0.87

Hydrophobicity -0.410

Aliphatic Index 52.33

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 13980

Absorbance 280nm 450.90

Polar Residues 9

number

5

A

0

R

1

N

2

D

0

C

0

E

2

Q

2

G

0

H

1

I

1

L

2

K

0

M

1

F

2

P

1

S

3

T

2

W

2

Y

1

V

Amino Acid Distribution

A: 5 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 1 L: 1 K: 2 M: 0 F: 1 P: 2 S: 1 T: 3 W: 2 Y: 2 V: 1

Length

30

Formula

C144H207N35O42

Mass

3100.44

PI

6.76

Net Charge

-0

Boman Index

-0.87

Hydrophobicity

-0.410

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.