Back to search

Peptide record

TPDB49531

Antifungal standard
208 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB49531
Antifungal
Anti-infective peptides
CAFPdb dbAMP
standard
No
A 208-aa standard-residue antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.
Sequence
SGVFEVHNNCPYTVWAAATPVGGGRRLERGQSWWFWAPPGTKMARIWGRTNCNFDGAGRGWCQTGDCGGVLECKGWGKPPNTLAEYALNQFSNLDFWDISVIDGFNIPMSFGPTKPGPGKCHGIQCTANINGECPGSLRVPGGCNNPCTTFGGQQYCCTQGPCGPTELSRWFKQRCPDAYSYPQDDPTSTFTCTSWTTDYKVMFCPYG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1005H1469N277O295S19
G
22760.54
7.20
18
15
62
+0
1.38
-0.477
40.34
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
66430
2.92
72
Residue Composition
number
10
A
9
R
12
N
9
D
16
C
6
E
9
Q
29
G
2
H
6
I
7
L
7
K
3
M
11
F
19
P
10
S
18
T
10
W
7
Y
8
V
Amino Acid Distribution
A: 10 R: 9 N: 12 D: 9 C: 16 E: 6 Q: 9 G: 29 H: 2 I: 6 L: 7 K: 7 M: 3 F: 11 P: 19 S: 10 T: 18 W: 10 Y: 7 V: 8
Chemical Descriptors
208 reviewed residue count
C1005H1469N277O295S19 sequence-only estimate (linear, free termini)
22760.54 sequence-only estimate (linear, free termini)
7.20 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
1.38 sequence-only estimate (linear, free termini)
-0.477 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.