TPDB

3D PDB MODEL

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TPDB ID TPDB49530

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

CAFPdb dbAMP

Sequence_Type

standard

Has_Modification No

Description A 255-aa standard natural antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.

Sequence

QQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCGVRTVGEIVVGDIGGIISKGMFNNILKHRDDDACEGKGFYTYEAFVAAARSFPAFGSTGDDATRKREIAAFLAQTSHETSAGWPSAPDGPYAWGYCFVRERNPPSKYCDTTTPCPKSYYGRGPIQLTWNYNYEQAGRAIGADLLNNPDLVATDAVISFKTAIWFWMTAQSSKPSCHDVITGSWRPSASDNSVCHVPDYAVVTNIISGEIEY

FASTA

>TPDB49530|Antifungal|length=255
QQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCGVRTVGEIVVGDIGGIISKGMFNNILKHRDDDACEGKGFYTYEAFVAAARSFPAFGSTGDDATRKREIAAFLAQTSHETSAGWPSAPDGPYAWGYCFVRERNPPSKYCDTTTPCPKSYYGRGPIQLTWNYNYEQAGRAIGADLLNNPDLVATDAVISFKTAIWFWMTAQSSKPSCHDVITGSWRPSASDNSVCHVPDYAVVTNIISGEIEY

Formula C1216H1839N349O379S18

Absent Amino Acids

Common Amino Acids AG

Mass 27988.17

PI 6.85

Basic Residues 28

Acidic Residues 24

Hydrophobic Residues 89

Net Charge -0

Boman Index 34.89

Hydrophobicity -0.429

Aliphatic Index 56.31

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 54860

Absorbance 280nm 196.01

Polar Residues 91

number

24

A

16

R

13

N

14

D

16

C

10

E

11

Q

24

G

4

H

14

I

7

L

8

K

2

M

9

F

13

P

20

S

17

T

6

W

14

Y

13

V

Amino Acid Distribution

A: 24 R: 16 N: 13 D: 14 C: 16 E: 10 Q: 11 G: 24 H: 4 I: 14 L: 7 K: 8 M: 2 F: 9 P: 13 S: 20 T: 17 W: 6 Y: 14 V: 13

Length

255

Formula

C1216H1839N349O379S18

Mass

27988.17

PI

6.85

Net Charge

-0

Boman Index

34.89

Hydrophobicity

-0.429

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.