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Peptide record

TPDB49529

Antifungal standard
230 amino acids
Basic Information
3D PDB MODEL
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TPDB49529
Antifungal
Anti-infective peptides
CAFPdb dbAMP
standard
No
A 230-aa standard-residue antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.
Sequence
SGVFEVHNNCPYTVWAAATPVGGGRRLERGQSWWFWAPPGTKMARIWGRTNCNFDGAGRGWCQTGDCGGVLECKGWGKPPNTLAEYALNQFSNLDFWDISVIDGFNIPMSFGPTKPGPGKCHGIQCTANINGECPGSLRVPGGCNNPCTTFGGQQYCCTQGPCGPTELSRWFKQRCPDAYSYPQDDPTSTFTCTSWTTDYKVMFCPYGSAHNETTNFPLEMPTSTHEVAK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1109H1628N306O331S20
G
25184.18
6.42
21
18
68
-1
1.46
-0.514
40.30
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
66430
2.64
80
Residue Composition
number
12
A
9
R
14
N
9
D
16
C
9
E
9
Q
29
G
4
H
6
I
8
L
8
K
4
M
12
F
21
P
12
S
22
T
10
W
7
Y
9
V
Amino Acid Distribution
A: 12 R: 9 N: 14 D: 9 C: 16 E: 9 Q: 9 G: 29 H: 4 I: 6 L: 8 K: 8 M: 4 F: 12 P: 21 S: 12 T: 22 W: 10 Y: 7 V: 9
Chemical Descriptors
230 reviewed residue count
C1109H1628N306O331S20 sequence-only estimate (linear, free termini)
25184.18 sequence-only estimate (linear, free termini)
6.42 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
1.46 sequence-only estimate (linear, free termini)
-0.514 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.