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Peptide record

TPDB49525

Antifungal standard
226 amino acids
Basic Information
3D PDB MODEL
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TPDB49525
Antifungal
Anti-infective peptides
CAFPdb dbAMP
standard
No
A 226-aa standard-residue antifungal peptide sequence curated from CAFPdb and dbAMP, with an available 3D structural model.
Sequence
ATIEVRNNCPYTVWAASTPIGGGRRLNRGQTWVINAPRGTKMARIWGRTGCNFNAAGRGTCQTGDCGGVLQCTGWGKPPNTLAEYALDQFSNLDFWDISLVDGFNIPMTFAPTKPSGGKCHAIHCTANINGECPRALKVPGGCNNPCTTFGGQQYCCTQGPCGPTELSKFFKKRCPDAYSYPQDDPTSTFTCPGGSTNYRVVFCPNGVADPNFPLEMPASTDEVAK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C1054H1607N301O320S19
G
24224.32
7.85
22
16
69
+3
1.49
-0.403
49.69
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
37440
1.55
77
Residue Composition
number
17
A
11
R
16
N
10
D
16
C
6
E
8
Q
27
G
2
H
8
I
9
L
9
K
3
M
11
F
21
P
9
S
22
T
5
W
6
Y
10
V
Amino Acid Distribution
A: 17 R: 11 N: 16 D: 10 C: 16 E: 6 Q: 8 G: 27 H: 2 I: 8 L: 9 K: 9 M: 3 F: 11 P: 21 S: 9 T: 22 W: 5 Y: 6 V: 10
Chemical Descriptors
226 reviewed residue count
C1054H1607N301O320S19 sequence-only estimate (linear, free termini)
24224.32 sequence-only estimate (linear, free termini)
7.85 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.49 sequence-only estimate (linear, free termini)
-0.403 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.