Peptide record

TPDB49524

Antifungal standard
157 amino acids
Basic Information
3D PDB MODEL
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TPDB49524
Antifungal
Anti-infective peptides
CAFPdb
standard
No
A 157-aa standard natural antifungal peptide sequence curated from CAFPdb, with an available 3D structural model.
Sequence
MSLLQRSMVLVAAVFCLSAIYVSAEAEVDANCLGCMCEAATRCNASTACHNSGGGYFCGPFHISWAYWADAGKPVLLHDDPNRLGAFEDCAKDLYCSATVVRQYMKKFAKDCDGDGVVTCKDYVRLHKLGRQGCTVPLPQDRFTTQFEECAKRLNVY
Physicochemical Analysis
C754H1165N209O224S17
A
17286.83
6.42
20
17
66
-1
20.99
-0.025
72.74
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
22180
128.31
45
Residue Composition
number
18
A
8
R
5
N
11
D
13
C
6
E
5
Q
11
G
4
H
2
I
13
L
8
K
4
M
7
F
5
P
8
S
7
T
2
W
7
Y
13
V
Amino Acid Distribution
A: 18 R: 8 N: 5 D: 11 C: 13 E: 6 Q: 5 G: 11 H: 4 I: 2 L: 13 K: 8 M: 4 F: 7 P: 5 S: 8 T: 7 W: 2 Y: 7 V: 13
Chemical Descriptors
157
C754H1165N209O224S17
17286.83
6.42
-1
20.99
-0.025
Evidence Records 1 records
Evidence 1 Activity

Activity

MIC
Antifungal
18.4 µM

Target

V. alginolyticus

Source & Reference

CAFPdb

Other

Active against Gram- V. alginolyticus (MIC 18.4 uM). This atypical lysozyme Splys-i is an anionic protein without muramidase activity of norm