TPDB

3D PDB MODEL

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TPDB ID TPDB49505

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 58-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, DRAMP, and other sources, with an available 3D structural model.

Sequence

YNVENGGSLCCNNHPKFGKCNTKNDDQRCNSWCLNGCDNGKGGYCKSMSHGGQCHCYC

FASTA

>TPDB49505|Antifungal|length=58
YNVENGGSLCCNNHPKFGKCNTKNDDQRCNSWCLNGCDNGKGGYCKSMSHGGQCHCYC

Formula C255H384N84O86S11

Absent Amino Acids AI

Common Amino Acids C

Mass 6355.03

PI 7.73

Basic Residues 9

Acidic Residues 4

Hydrophobic Residues 9

Net Charge +2

Boman Index 11.01

Hydrophobicity -1.009

Aliphatic Index 18.45

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 10595

Absorbance 280nm 166.72

Polar Residues 29

number

0

A

1

R

9

N

3

D

10

C

1

E

2

Q

9

G

3

H

0

I

2

L

5

K

1

M

1

F

1

P

4

S

1

T

1

W

3

Y

1

V

Amino Acid Distribution

A: 0 R: 1 N: 9 D: 3 C: 10 E: 1 Q: 2 G: 9 H: 3 I: 0 L: 2 K: 5 M: 1 F: 1 P: 1 S: 4 T: 1 W: 1 Y: 3 V: 1

Length

58

Formula

C255H384N84O86S11

Mass

6355.03

PI

7.73

Net Charge

+2

Boman Index

11.01

Hydrophobicity

-1.009

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.