TPDB

3D PDB MODEL

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TPDB ID TPDB49504

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Antifungipept CAFPdb dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 49-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, dbAMP, and other sources, with an available 3D structural model.

Sequence

YCERSSGTWSGVCGNTDKCSSQCQRLEGAAHGSCNYVFPAHKCICYYPC

FASTA

>TPDB49504|Antifungal|length=49
YCERSSGTWSGVCGNTDKCSSQCQRLEGAAHGSCNYVFPAHKCICYYPC

Formula C225H334N66O72S8

Absent Amino Acids M

Common Amino Acids C

Mass 5372.01

PI 7.51

Basic Residues 6

Acidic Residues 3

Hydrophobic Residues 13

Net Charge +1

Boman Index 4.90

Hydrophobicity -0.414

Aliphatic Index 33.88

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 11960

Absorbance 280nm 222.64

Polar Residues 24

number

3

A

2

R

2

N

1

D

8

C

2

E

2

Q

5

G

2

H

1

I

1

L

2

K

0

M

1

F

2

P

6

S

2

T

1

W

4

Y

2

V

Amino Acid Distribution

A: 3 R: 2 N: 2 D: 1 C: 8 E: 2 Q: 2 G: 5 H: 2 I: 1 L: 1 K: 2 M: 0 F: 1 P: 2 S: 6 T: 2 W: 1 Y: 4 V: 2

Length

49

Formula

C225H334N66O72S8

Mass

5372.01

PI

7.51

Net Charge

+1

Boman Index

4.90

Hydrophobicity

-0.414

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.