TPDB

3D PDB MODEL

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TPDB ID TPDB49503

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Antifungipept CAFPdb dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 49-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, dbAMP, and other sources, with an available 3D structural model.

Sequence

YCERSSGTWSGVCGNSGKCSNQCQRLEGAAHGSCNYVFPAHKCICYYPC

FASTA

>TPDB49503|Antifungal|length=49
YCERSSGTWSGVCGNSGKCSNQCQRLEGAAHGSCNYVFPAHKCICYYPC

Formula C223H331N67O70S8

Absent Amino Acids DM

Common Amino Acids C

Mass 5326.97

PI 7.85

Basic Residues 6

Acidic Residues 2

Hydrophobic Residues 13

Net Charge +2

Boman Index 3.96

Hydrophobicity -0.408

Aliphatic Index 33.88

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 11960

Absorbance 280nm 224.52

Polar Residues 24

number

3

A

2

R

3

N

0

D

8

C

2

E

2

Q

6

G

2

H

1

I

1

L

2

K

0

M

1

F

2

P

6

S

1

T

1

W

4

Y

2

V

Amino Acid Distribution

A: 3 R: 2 N: 3 D: 0 C: 8 E: 2 Q: 2 G: 6 H: 2 I: 1 L: 1 K: 2 M: 0 F: 1 P: 2 S: 6 T: 1 W: 1 Y: 4 V: 2

Length

49

Formula

C223H331N67O70S8

Mass

5326.97

PI

7.85

Net Charge

+2

Boman Index

3.96

Hydrophobicity

-0.408

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.