TPDB

3D PDB MODEL

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TPDB ID TPDB49476

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 64-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, DRAMP, and other sources, with an available 3D structural model.

Sequence

SRNKLSSYIPLCGSNTYCGGLWCPKKGGKYSCISMSCDIQEDCPKLVRCKNSPGPYCMEGFCTC

FASTA

>TPDB49476|Antifungal|length=64
SRNKLSSYIPLCGSNTYCGGLWCPKKGGKYSCISMSCDIQEDCPKLVRCKNSPGPYCMEGFCTC

Formula C297H467N81O91S12

Absent Amino Acids AH

Common Amino Acids C

Mass 7013.18

PI 8.14

Basic Residues 8

Acidic Residues 4

Hydrophobic Residues 16

Net Charge +4

Boman Index 6.84

Hydrophobicity -0.322

Aliphatic Index 47.19

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12085

Absorbance 280nm 172.32

Polar Residues 28

number

0

A

2

R

3

N

2

D

10

C

2

E

1

Q

7

G

0

H

3

I

4

L

6

K

2

M

1

F

5

P

8

S

2

T

1

W

4

Y

1

V

Amino Acid Distribution

A: 0 R: 2 N: 3 D: 2 C: 10 E: 2 Q: 1 G: 7 H: 0 I: 3 L: 4 K: 6 M: 2 F: 1 P: 5 S: 8 T: 2 W: 1 Y: 4 V: 1

Length

64

Formula

C297H467N81O91S12

Mass

7013.18

PI

8.14

Net Charge

+4

Boman Index

6.84

Hydrophobicity

-0.322

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.