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Peptide record

TPDB49451

Antifungal standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB49451
Antifungal
Anti-infective peptides
Antifungipept CAFPdb dbAMP Peptipedia
standard
No
A 51-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
QRLCEKPSGTWSGVCGNNGACRNQCIRLEKARHGSCNYVFPAHKCICYFPC
Physicochemical Analysis
C242H375N77O68S8
DM
C
5707.59
8.52
9
2
14
+5
6.92
-0.422
47.84
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8980
157.33
20
Residue Composition
number
3
A
4
R
4
N
0
D
8
C
2
E
2
Q
5
G
2
H
2
I
2
L
3
K
0
M
2
F
3
P
3
S
1
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 3 R: 4 N: 4 D: 0 C: 8 E: 2 Q: 2 G: 5 H: 2 I: 2 L: 2 K: 3 M: 0 F: 2 P: 3 S: 3 T: 1 W: 1 Y: 2 V: 2
Chemical Descriptors
51
C242H375N77O68S8
5707.59
8.52
+5
6.92
-0.422
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antifungal
0.6 µM

Target

F. oxysporum

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against the filamentous fungus F. oxysporum (MIC 0.6 uM), A. brassicola (MIC 2.5 uM), S-cerevisiae (MIC > 20 uM), C-albicans (MIC >20 ug/ml), E-co
Evidence 2 Activity

Activity

MIC
Antifungal
2.5 µM

Target

A. brassicola

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against the filamentous fungus F. oxysporum (MIC 0.6 uM), A. brassicola (MIC 2.5 uM), S-cerevisiae (MIC > 20 uM), C-albicans (MIC >20 ug/ml), E-coli (MIC>20 uM), and M. luteu
Evidence 3 Activity

Activity

MIC
Antifungal
15 µM

Target

M. luteus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

2.5 uM), S-cerevisiae (MIC > 20 uM), C-albicans (MIC >20 ug/ml), E-coli (MIC>20 uM), and M. luteus (MIC 15 uM).