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Peptide record

TPDB49450

Antifungal standard
125 amino acids
Basic Information
3D PDB MODEL
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TPDB49450
Antifungal
Anti-infective peptides
Antifungipept CAFPdb dbAMP Peptipedia
standard
No
A 125-aa standard-residue antifungal peptide sequence curated from Antifungipept, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
QQATNVRATYHYYRPAQNNWDLGAPAVSAYCATWDASKPLSWRSKYGWTAFCGPAGAHGQASCGKCLQVTNPATGAQITARIVDQCANGGLDLDWDTVFTKIDTNGIGYQQGHLNVNYQFVDCRD
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C600H893N173O184S6
EM
A
13666.10
7.00
12
9
48
+0
1.56
-0.458
60.24
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
38305
2.80
46
Residue Composition
number
16
A
5
R
8
N
9
D
6
C
0
E
10
Q
12
G
3
H
4
I
6
L
4
K
0
M
3
F
5
P
5
S
10
T
5
W
7
Y
7
V
Amino Acid Distribution
A: 16 R: 5 N: 8 D: 9 C: 6 E: 0 Q: 10 G: 12 H: 3 I: 4 L: 6 K: 4 M: 0 F: 3 P: 5 S: 5 T: 10 W: 5 Y: 7 V: 7
Chemical Descriptors
125 reviewed residue count
C600H893N173O184S6 sequence-only estimate (linear, free termini)
13666.10 sequence-only estimate (linear, free termini)
7.00 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
1.56 sequence-only estimate (linear, free termini)
-0.458 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.