TPDB

3D PDB MODEL

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TPDB ID TPDB49443

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 46-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, DRAMP, and other sources, with an available 3D structural model.

Sequence

QESKKGILLKPKTCNTNADCAKFCKGPIQNCLYHTCACVPGNPHCC

FASTA

>TPDB49443|Antifungal|length=46
QESKKGILLKPKTCNTNADCAKFCKGPIQNCLYHTCACVPGNPHCC

Formula C210H340N62O62S8

Absent Amino Acids RMW

Common Amino Acids C

Mass 4981.87

PI 8.31

Basic Residues 8

Acidic Residues 2

Hydrophobic Residues 11

Net Charge +4

Boman Index 9.60

Hydrophobicity -0.365

Aliphatic Index 55.22

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 1990

Absorbance 280nm 39.94

Polar Residues 19

number

3

A

0

R

4

N

1

D

8

C

1

E

2

Q

3

G

2

H

2

I

3

L

6

K

0

M

1

F

4

P

1

S

3

T

0

W

1

Y

1

V

Amino Acid Distribution

A: 3 R: 0 N: 4 D: 1 C: 8 E: 1 Q: 2 G: 3 H: 2 I: 2 L: 3 K: 6 M: 0 F: 1 P: 4 S: 1 T: 3 W: 0 Y: 1 V: 1

Length

46

Formula

C210H340N62O62S8

Mass

4981.87

PI

8.31

Net Charge

+4

Boman Index

9.60

Hydrophobicity

-0.365

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.